Uric Acid In Urine: What Affects The Test


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What Affects the Test


  • Women generally have slightly lower uric acid levels than men.
  • Many medicines may increase the level of uric acid in the urine. These include some diuretics, vitamin C (ascorbic acid), aspirin, probenecid (such as Probalan), and some medicines used to treat leukemia, lymphoma, or tuberculosis.
  • Some medicines may decrease the level of uric acid in the urine. These include allopurinol (such as Aloprim and Zyloprim), insulin, and some diuretics.
  • Drinking alcohol during the collection period will decrease the level of uric acid in the urine.
  • Failing to collect exactly 24 hours of urine during a uric acid urine test can cause inaccurate test results.
  • Strenuous exercise or a diet high in purines (such as liver, kidney, peas or beans, and some fish) can increase levels of uric acid in the urine.
  • Contrast material used for some X-ray tests can increase the amount of uric acid in the urine.


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Last updated: October 31, 2007
Author: Maria G. Essig, MS, ELS
Reviewed By: E. Gregory Thompson, MD - Internal Medicine, Stanford M. Shoor, MD - Rheumatology
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

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