Total Serum Protein: Results


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Results


A total serum protein test is a blood test that measures the amounts of total protein, albumin, and globulin in the blood. Results are usually available within 12 hours.

Normal

Normal values may vary from lab to lab.

Total serum protein

Total protein:

5.5–9.0 grams per deciliter (g/dL)

Albumin:

3.5–5.5 g/dL

Globulin:

2.0–3.5 g/dL

Albumin/globulin ratio:

Greater than 1.0

High values

High albumin levels may be caused by:

High globulin levels may be caused by:

Low values

Low albumin levels may be caused by:

  • A poor diet (malnutrition).
  • Severe burns.
  • Kidney disease.
  • Liver disease.
  • An autoimmune disease, such as systemic lupus erythematosus (SLE) or rheumatoid arthritis.
  • Gastrointestinal malabsorption syndromes, such as sprue or Crohn's disease.
  • Hodgkin's lymphoma.
  • Uncontrolled diabetes.
  • Hyperthyroidism.
  • Heart failure.


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Last updated: January 02, 2008
Author: Maria G. Essig, MS, ELS
Reviewed By: Kathleen Romito, MD - Family Medicine, Jerome B. Simon, MD, FRCPC, FACP - Gastroenterology
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

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