Skin Biopsy


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A skin biopsy is a procedure in which a sample of skin tissue is removed, processed, and examined under a microscope.

Several different methods may be used to obtain a skin sample, depending on the size and location of the abnormal area of skin, called a skin lesion. The skin sample is placed in a solution, such as formaldehyde, or in a sterile container if infection is suspected. In each of these procedures, the tissue is processed and then examined under a microscope.

Skin biopsies most often are done to diagnose skin cancer, which may be suspected when an abnormal area of skin has changed color Click here to see an illustration., shape Click here to see an illustration., size, or appearance or has not healed after an injury. Skin cancers are the most common type of cancers.

Early diagnosis of a suspicious skin lesion and skin biopsy can help identify skin cancers and lead to early treatment.

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Last updated: April 26, 2007
Author: Maria G. Essig, MS, ELS
Reviewed By: Kathleen Romito, MD - Family Medicine, Alexander H. Murray, MD, FRCPC - Dermatology
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

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