Semen Analysis: What Affects The Test


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What Affects the Test


Factors that can interfere with your test or the accuracy of the results include:

  • Medicines, such as cimetidine (Tagamet), male and female hormones (testosterone, estrogen), sulfasalazine, nitrofurantoin, and some chemotherapy medicines.
  • Caffeine, alcohol, cocaine, marijuana, and smoking tobacco.
  • Herbal medicines, such as St. John's wort and high doses of echinacea.
  • A semen sample that gets cold. The sperm motility value will be inaccurately low if the semen sample gets cold.
  • Exposure to radiation, some chemicals (such as certain pesticides or spermicides), and prolonged heat exposure.
  • An incomplete semen sample. This is more common if a sample is collected by methods other than masturbation.
  • Not ejaculating for several days. This may affect the semen volume.


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Last updated: February 20, 2007
Author: Maria G. Essig, MS, ELS
Reviewed By: Martin Gabica, MD - Family Medicine, Avery L. Seifert, MD - Urology
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

This information is not intended to replace the advice of a doctor. By using AOL Body, you indicate that you have read, understood, and agreed to our Terms of Service, and AOL Body Advertising Policy. Read more about our content partners.

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