Rheumatoid Factor (RF): What To Think About


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What To Think About


  • A small number of people have a high RF level but do not have rheumatoid arthritis. A small number of these people will later have rheumatoid arthritis.
  • A health professional always uses the results of an RF test along with information gained from a medical history and physical examination before diagnosing rheumatoid arthritis.
  • Cyclic citrullinated peptide (CCP) is an antibody that is found in the blood of more than half of all people who have rheumatoid arthritis. It is used to confirm a diagnosis of rheumatoid arthritis.
  • Older adults who do not have rheumatoid arthritis sometimes have a slightly high RF level.
  • Some people have rheumatoid arthritis and have a normal level of RF. The RF test may need to be repeated if rheumatoid arthritis is suspected and the first RF level was normal.
  • Less than one-third of children who have juvenile rheumatoid arthritis have a high RF level.


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Last updated: June 12, 2008
Author: Shannon Erstad, MBA/MPH
Reviewed By: Kathleen Romito, MD - Family Medicine, Stanford M. Shoor, MD - Rheumatology
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

This information is not intended to replace the advice of a doctor. By using AOL Body, you indicate that you have read, understood, and agreed to our Terms of Service, and AOL Body Advertising Policy. Read more about our content partners.

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