Lymph Node Biopsy: How It Feels


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How It Feels


You will feel only a quick sting from the needle if you have a local anesthesia to numb the skin. You may feel some pressure when the biopsy needle is put in. After a fine-needle aspiration biopsy or core needle biopsy, the site may be tender for 2 to 3 days. You also may have a bruise around the site.

If you have general anesthesia for an open lymph node biopsy, you will not be awake during the biopsy. After you wake up, the area may be numb from a local anesthetic that was put into the biopsy site. You will also feel sleepy for several hours.

For 1 to 2 days after an open lymph node biopsy, you may feel tired. You may also have a mild sore throat from the tube that was used to help you breathe during the biopsy. Using throat lozenges and gargling with warm salt water may help with the sore throat.

After an open biopsy, the area may feel tender, firm, swollen, and bruised. You may have fluid collect near the biopsy site. You may also have fluid leak from the biopsy site. The tenderness should go away in about a week, and the bruising usually fades within 2 weeks. However, the firmness and swelling may last for 6 to 8 weeks. Do not do any heavy lifting or other activities that stretch or pull the muscles around the area.



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Last updated: May 01, 2007
Author: Maria G. Essig, MS, ELS
Reviewed By: Anne C. Poinier, MD - Internal Medicine, Brent Shoji, MD - General Surgery
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

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