Breast Biopsy

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Test Overview

A breast biopsy removes a sample of breast tissue that is looked at under a microscope to check for breast cancer. A breast biopsy is usually done to check a lump found during a breast examination or a suspicious area found on a mammogram or ultrasound. See an illustration of the female breast .

There are several ways to do a breast biopsy. The sample of breast tissue will be looked at under a microscope to check for cancer cells.

• A fine-needle aspiration biopsy puts a thin needle through the skin, into the lump, and removes cells to look at. Needle aspiration may be done to see if the lump is solid or fluid-filled (cyst). If the lump is a cyst, it will go away after the fluid is removed. If there is no fluid, another type of biopsy will be done.
• A core needle biopsy uses a large needle fitted with a special tip. The needle goes through the skin to the lump or area to take out a sample of tissue about the size of a pencil lead. A core needle biopsy can also be done using a suction unit that gently removes a larger sample of tissue.
• A stereotactic biopsy uses a special type of X-ray during a core needle biopsy to find the area of the breast where the biopsy sample will be taken. This technique can check a lump that cannot be felt on breast examination but is seen on mammogram or ultrasound. A small incision is then made in the skin of the breast, and the core needle is guided by the X-ray to the biopsy site to take a tissue sample. Stereotactic biopsy may not be appropriate for all types of breast lumps.
• An open biopsy makes a cut in the skin and removes a sample of the lump or the entire lump. If your doctor cannot feel a lump, a needle (or wire) can be put in the suspicious area during a mammogram done just before surgery. The needle (or wire) then guides your doctor to the suspicious area to take a biopsy sample.

More tests or biopsies may be needed if problems are found during the first biopsy or if your doctor is concerned about a certain area of your breast.

Last updated:	May 01, 2007
Author:	Maria G. Essig, MS, ELS
Reviewed By:	Anne C. Poinier, MD - Internal Medicine, Brent Shoji, MD - General Surgery
Editors:	Susan Van Houten, RN, BSN, MBA, Tracy Landauer