Antinuclear Antibodies (ANA): What To Think About


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What To Think About


  • Autoimmune diseases cannot be diagnosed by the results of the ANA test alone. A complete medical history, physical examination, and the results are other tests are used with the ANA test to help identify autoimmune diseases, such as systemic lupus erythematosus (SLE) or rheumatoid arthritis.
  • Some healthy people can have an increased ANA titer. For instance, some people with a family history of autoimmune disease may have a high ANA titer. The higher the titer, however, the more likely it is that the person has an autoimmune disease.
  • ANA levels can increase as a person ages.


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Last updated: June 12, 2008
Author: Shannon Erstad, MBA/MPH
Reviewed By: Kathleen Romito, MD - Family Medicine, Stanford M. Shoor, MD - Rheumatology
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

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