Antinuclear Antibodies (ANA)


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Test Overview


An antinuclear antibody (ANA) test measures the amount and pattern of antibodies in your blood that work against your own body (autoimmune).

The body's immune system normally attacks and destroys foreign substances such as bacteria and viruses. However, in disorders known as autoimmune diseases, the immune system attacks and destroys the body's normal tissues. When a person has an autoimmune disease, the immune system Click here to see an illustration. produces antibodies that attach to the body's own cells as though they were foreign substances, often causing them to be damaged or destroyed. Rheumatoid arthritis and systemic lupus erythematosus are examples of autoimmune diseases.

An ANA test is used along with your symptoms, physical examination, and other tests to find an autoimmune disease.

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Last updated: June 16, 2006
Author: Sydney Youngerman-Cole, RN, BSN, RNC
Reviewed By: Kathleen Romito, MD - Family Medicine, Stanford M. Shoor, MD - Rheumatology
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

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