Amylase: What Affects The Test


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What Affects the Test


Factors that can interfere with your test or the accuracy of the results include:

  • Medicines, including narcotics such as codeine and morphine, birth control pills, diuretics, indomethacin (Indocin), and blood-thinning medicines, such as warfarin (Coumadin) and aspirin.
  • Hepatitis, cirrhosis, or extensive damage to the pancreas.
  • Chronic pancreatitis, which may be present even though amylase levels are low.
  • Blood in the urine. If you are a woman who has menstrual periods, you may need to schedule a urine test for amylase when you are not having your period.
  • Drinking a large amount of alcohol before the test.
  • Saliva, which contains large amounts of amylase. Coughing, sneezing, or even talking over an uncovered urine or blood specimen can contaminate the specimen and artificially increase amylase values.
  • Chronic kidney disease, which may cause high levels when the kidneys are no longer able to remove amylase from the blood.


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Last updated: April 30, 2007
Author: Ralph Poore
Reviewed By: Anne C. Poinier, MD - Internal Medicine, Peter J. Kahrilas, MD - Gastroenterology
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

This information is not intended to replace the advice of a doctor. By using AOL Body, you indicate that you have read, understood, and agreed to our Terms of Service, and AOL Body Advertising Policy. Read more about our content partners.

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