Amniocentesis: What Affects The Test


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What Affects the Test


Reasons you may not be able to have the test or why the results may not be helpful include:

  • If there is blood from your fetus in the amniotic fluid. This can falsely increase the level of the substances alpha-fetoprotein (AFP) and acetylcholinesterase (AChE) levels, which test for neural tube defects.
  • If the amniotic fluid is exposed to light. This can falsely lower bilirubin levels.
  • If there is blood or meconium in the fluid. This may cause an incorrect result for the test that checks to see whether your baby’s (fetus’s) lungs are mature.


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Last updated: May 14, 2008
Author: Sandy Jocoy, RN
Reviewed By: Sarah Marshall, MD - Family Medicine, Siobhan M. Dolan, MD, MPH - Reproductive Genetics
Editors: Kathleen M. Ariss, MS, Tracy Landauer

This information is not intended to replace the advice of a doctor. By using AOL Body, you indicate that you have read, understood, and agreed to our Terms of Service, and AOL Body Advertising Policy. Read more about our content partners.

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