Alkaline Phosphatase


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Test Overview


An alkaline phosphatase (ALP) test measures the amount of the enzyme ALP in the blood. ALP is made mostly in the liver Click here to see an illustration. and in bone with some made in the intestines Click here to see an illustration. and kidneys Click here to see an illustration.. It also is made by the placenta of a pregnant woman.

The liver makes more ALP than the other organs or the bones. Some conditions cause large amounts of ALP in the blood. These conditions include rapid bone growth (during puberty), bone disease (osteomalacia or Paget's disease), or a disease that affects how much calcium is in the blood (hyperparathyroidism), or damaged liver cells.

If the ALP level is high, more tests may be done to find the cause.

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Last updated: July 28, 2008
Author: Caroline Rea, RN, BS, MS
Reviewed By: Caroline S. Rhoads, MD - Internal Medicine, Alan C. Dalkin, MD - Endocrinology
Editors: Maria Essig, Tracy Landauer

This information is not intended to replace the advice of a doctor. By using AOL Body, you indicate that you have read, understood, and agreed to our Terms of Service, and AOL Body Advertising Policy. Read more about our content partners.

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