Adrenocorticotropic Hormone: Results


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Results


An adrenocorticotropic hormone test measures the level of adrenocorticotropic hormone (ACTH) in the blood.

Results of an ACTH test are usually available in 4 to 6 days.

Normal

Normal values vary widely from lab to lab.

Normal ACTH levels
6 a.m. to 8 a.m.

Less than 80 pg/mL or less than 18 pmol/L

6 p.m. to 11 p.m.

Less than 50 pg/mL or less than 11 pmol/L

High values

High levels of ACTH may be caused by:

Low values

Low levels of ACTH may be caused by:

  • Damage to the pituitary gland from surgery, radiation, stroke, head injury, or a tumor.
  • An increased amount of cortisol from a tumor in the adrenal glands (Cushing's syndrome).
ACTH and cortisol levels in specific conditions
Condition ACTH Cortisol

Cushing's disease

High

High

Cushing's syndrome

Low

High

ACTH made outside the pituitary gland

High

High

Addison's disease

High

Low

Hypopituitarism

Low

Low



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Last updated: June 26, 2008
Author: Bets Davis, MFA
Reviewed By: Caroline S. Rhoads, MD - Internal Medicine, David C.W. Lau, MD, PhD, FRCPC - Endocrinology & Metabolism
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

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