Gene Therapy - On The Horizon: Improving Memory Understanding Age Related Memory Loss
Content provided by the Faculty of the Harvard Medical School
Gene therapy
Scientists are also experimenting with gene therapy as a means of restoring some of the neuronal connections that are destroyed by Alzheimer's disease and other neurological disorders. Operating on eight people with mild Alzheimer's, researchers at the University of California at San Diego genetically engineered some of the patients' own skin cells to release nerve growth factor. The cells were transplanted into several areas of the patients' brains. The therapy was successful in six of the patients. The rate of cognitive decline fell by 40%–50%, a better result than is possible with currently available medicines. PET scans showed increased metabolic activity in the areas of the brain with the implants, suggesting a positive effect. However, the gene therapy will have to be performed on more people to ensure that it is beneficial, a process that could take many years.
| Last updated: | January 23, 2007 |
|---|
Medical content reviewed by the Faculty of the Harvard Medical School. Harvard Health Publications, Copyright © 2007 by President and Fellows of Harvard College. All rights reserved. Used with permission of StayWell.
This information is not intended to replace the advice of a doctor. By using AOL Body, you indicate that you have read, understood, and agreed to our Terms of Service, Use of Content Agreement and AOL Body Advertising Policy. Read more about our content partners.
Search
Where Does it Hurt?
If you're experiencing aches and pains we can help you find answers. Find out what your symptoms mean for your health.
