Tiagabine for epilepsy
Content provided by Healthwise
Examples
| Brand Name | Chemical Name |
| Gabitril | tiagabine |
Tiagabine requires several oral doses each day.
How It Works
Tiagabine increases the brain levels of a chemical messenger (neurotransmitter) called gamma-aminobutyric acid (GABA), which may prevent abnormal electrical activity in brain cells.
Why It Is Used
Tiagabine is used in combination with other antiepileptic medications in adults and children older than 12 years to control partial seizures.1
How Well It Works
When added to treatment with another antiepileptic drug, tiagabine is sometimes effective in reducing partial seizures in adults and children older than 12 years who have had trouble controlling seizures with other drug treatment. It is not helpful in reducing other types of seizures, such as primary generalized seizures or those in children with Lennox-Gastaut syndrome.1
Side Effects
Common side effects of tiagabine include:
- Dizziness.
- Headache.
- Sleepiness.
- Inability to concentrate.
- Tremor.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
- Side effects. Tiagabine seems to be well-tolerated by most people.
- Cost. Tiagabine is expensive.
For some people, tiagabine may produce side effects or carry risks, including an increased risk of birth defects, that are not fully known yet. Report any unexpected side effects or problems to your doctor.
It may take time and careful, controlled adjustments by you and your doctor to find the combination, schedule, and dosing of medication to best manage your epilepsy. The goal is to prevent seizures while causing as few unwanted side effects as possible. Once the most effective medication program is determined, it is important that you follow it exactly as prescribed.
Complete the new medication information form (PDF) (What is a PDF document?) to help you understand this medication.
References
Citations
Jarrar RG, Buchhalter JR (2003). Therapeutics in pediatric epilepsy, part 1: The new antiepileptic drugs and the ketogenic diet. Mayo Clinical Procedures, 78(3): 359–370.
Credits
| Author | Monica Rhodes |
| Editor | Kathleen M. Ariss, MS |
| Associate Editor | Pat Truman |
| Primary Medical Reviewer | Michael J. Sexton, MD - Pediatrics |
| Specialist Medical Reviewer | Steven C. Schachter, MD - Neurology |
| Last Updated | November 11, 2005 |
| Last updated: | November 11, 2005 |
|---|---|
| Author: | Monica Rhodes |
| Reviewed By: | Michael J. Sexton, MD - Pediatrics, Steven C. Schachter, MD - Neurology |
| Editors: | Kathleen M. Ariss, MS, Pat Truman |
© 1995-2007, Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
This information is not intended to replace the advice of a doctor. By using AOL Body, you indicate that you have read, understood, and agreed to our Terms of Service, and AOL Body Advertising Policy. Read more about our content partners.
Search
Where Does it Hurt?
If you're experiencing aches and pains we can help you find answers. Find out what your symptoms mean for your health.
