Sertraline: What Other Drugs Will Affect Sertraline

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What other drugs will affect sertraline?

Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with sertraline may cause you to bruise or bleed easily.

Before taking sertraline, tell your doctor if you are using any of the following medicines:

• tramadol (Ultram, Ultram ER, Ultracet);
• digitoxin (Crystodigin);
• phenytoin (Dilantin), valproate (Depacon, Depakene);
• lithium (Lithobid, Eskalith);
• a blood thinner such as warfarin (Coumadin);
• any other antidepressant such as amitriptyline (Elavil), citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), or paroxetine (Paxil);
• almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or
• heart rhythm medication such as flecainide (Tambocor), propafenone (Rhythmol), and others.

This list is not complete and there may be other drugs that can interact with sertraline. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Last updated:	July 23, 2008