Membrane stabilizers for cystic fibrosis


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Examples


Brand Name Chemical Name
Intalcromolyn sodium
Brand Name Chemical Name
Tiladenedocromil sodium

How It Works


Normally, the body reacts to allergies or infections by releasing substances that cause inflammation. By preventing the release of these substances, membrane stabilizers help minimize inflammation. This helps keep breathing tubes clear, making it easier to breathe.


Why It Is Used


Membrane stabilizers are used mainly for asthma and other lung diseases, but they may also work for people who have cystic fibrosis. Currently, there is not much research about membrane stabilizers as a treatment for people who have cystic fibrosis.


How Well It Works


More studies are needed about how well membrane stabilizers work compared to other treatments such as corticosteroids.


Side Effects


The side effects of membrane stabilizers are mild, so they may be used in children or others who cannot tolerate corticosteroids.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)


What To Think About


Both cromolyn (Intal) and nedocromil (Tilade) are expensive.

Complete the new medication information form (PDF) (What is a PDF document?) to help you understand this medication.


Credits


Author Debby Golonka, MPH
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Pat Truman
Primary Medical Reviewer Michael J. Sexton, MD

- Pediatrics
Specialist Medical Reviewer Susanna McColley, MD

- Pediatric Pulmonology
Last Updated June 26, 2007

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Last updated: June 26, 2007
Author: Debby Golonka, MPH
Reviewed By: Michael J. Sexton, MD - Pediatrics, Susanna McColley, MD - Pediatric Pulmonology
Editors: Susan Van Houten, RN, BSN, MBA, Pat Truman

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