Guaifenesin, Hydrocodone, And Phenylephrine: What Should I Discuss With My Healthcare Provider Before Taking Guaifenesin Hydrocodone And Phenylephrine


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What should I discuss with my healthcare provider before taking guaifenesin, hydrocodone, and phenylephrine?


donot Do not use this medication if you are allergic to guaifenesin, hydrocodone, or phenylephrine, or to other decongestants, diet pills, stimulants, or ADHD medications.
donot Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.
habit Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Before taking guaifenesin, hydrocodone, and phenylephrine, tell your doctor if you are allergic to any drugs, or if you have:

  • asthma, COPD, sleep apnea, or other breathing disorders;
  • heart disease or high blood pressure;
  • diabetes;
  • a thyroid disorder;
  • liver or kidney disease;
  • a seizure disorder;
  • Addison's disease or other adrenal gland disorders;
  • enlarged prostate, urination problems;
  • mental illness; or
  • a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

nopreg FDA pregnancy category C. This medication may be harmful to an unborn baby, and could cause addiction or withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
nobrfeed This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.



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Last updated: February 25, 2008

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