Estradiol Vaginal (local): What Other Drugs Will Affect Estradiol Vaginal Local

Content provided by Cerner Multum, Inc.

What other drugs will affect estradiol vaginal (local)?

Before using estradiol vaginal, tell your doctor if you are using any of the following drugs:

• St. John's wort;
• phenobarbital (Luminal, Solfoton);
• a blood thinner such as warfarin (Coumadin);
• ritonavir (Norvir);
• carbamazepine (Carbatrol, Tegretol);
• rifampin (Rifadin, Rifater, Rifamate, Rimactane); or
• antibiotics such as clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Erythrocin, Ery-Tab), ketoconazole (Nizoral), or itraconazole (Sporanox);

If you are using any of these drugs, you may not be able to use estradiol vaginal or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect estradiol vaginal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Last updated:	August 14, 2006