Zollinger-Ellison syndrome


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Zollinger-Ellison syndrome


Zollinger-Ellison syndrome is a rare condition in which a tumor called a gastrinoma forms in the pancreas or small intestine. The tumor releases a hormone called gastrin that causes production of excess stomach acid.

Almost all people with Zollinger-Ellison syndrome get an ulcer at some point, usually in the small intestine (duodenal ulcer). Ulcers produced by this disease are more difficult to cure than ulcers from other causes.

In about half of the people with Zollinger-Ellison syndrome, the tumors (gastrinomas) are cancerous and can spread to the lymph nodes and liver.

The main treatment for Zollinger-Ellison syndrome is removal of the tumors and taking acid-suppressing medication called proton pump inhibitors.

Credits


Author Monica Rhodes
Editor Kathleen M. Ariss, MS
Associate Editor Tracy Landauer
Primary Medical Reviewer Kathleen Romito, MD - Family Medicine
Specialist Medical Reviewer Peter J. Kahrilas, MD - Gastroenterology
Last Updated April 11, 2008

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Last updated: April 11, 2008
Author: Monica Rhodes
Reviewed By: Kathleen Romito, MD - Family Medicine, Peter J. Kahrilas, MD - Gastroenterology
Editors: Kathleen M. Ariss, MS, Tracy Landauer

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