Wernicke-Korsakoff syndrome

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Wernicke-Korsakoff syndrome

Wernicke-Korsakoff syndrome is a serious brain disorder that can develop in people who drink alcohol excessively over time. Symptoms include blurred vision, rapid movement of the eyes, and difficulty walking.

Wernicke-Korsakoff syndrome is a combination of two conditions: Wernicke syndrome and Korsakoff syndrome.

Wernicke syndrome is caused by thiamine (vitamin B1) deficiency. Symptoms such as blurred vision may go away if a person stops drinking and takes thiamine supplements.
Korsakoff syndrome is caused by changes in the brain that result from long-term alcohol use. Symptoms include confusion and memory loss, especially of recent events, which often lead the person to make up events (confabulation) to fill the memory gaps. The effects of Korsakoff syndrome may be permanent.

Treatment for Wernicke-Korsakoff syndrome includes replacement of thiamine, proper nutrition and body fluids (hydration), and avoiding alcohol use.

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Author	Jeannette Curtis
Author	Paul Lehnert
Editor	Roya Camp
Editor	Katy E. Magee, MA
Associate Editor	Terrina Vail
Primary Medical Reviewer	Adam Husney, MD - Family Medicine
Specialist Medical Reviewer	James R. McKay, PhD - Psychology
Last Updated	February 15, 2008

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Last updated:	February 15, 2008
Author:	Paul Lehnert
Reviewed By:	Adam Husney, MD - Family Medicine, James R. McKay, PhD - Psychology
Editors:	Katy E. Magee, MA, Terrina Vail

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