Wegener's Granulomatosis

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Important

It is possible that the main title of the report Wegener's Granulomatosis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

• Necrotizing Respiratory Granulomatosis
• Pathergic Granulomatosis
• Midline granulomatosis

Disorder Subdivisions

• None

General Discussion

Wegener's granulomatosis is an uncommon disorder characterized by inflammation of blood vessels (vasculitis) that results in damage to various organ systems of the body, most often the respiratory tract and kidneys. Symptoms may include ulcerations of the mucous membranes in the nose with secondary bacterial infection, a persistent runny nose, sinus pain, and chronic middle ear infection (otitis media) potentially resulting in hearing loss. In some cases, kidney abnormalities may progress to kidney failure, a serious complication. If the lungs are affected, a cough, expectoration of blood (hemoptysis), and inflammation of the thin membrane lining the outside of the lungs and the inside of the lung may be present. The exact cause of Wegener’s granulomatosis is not known.

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Resources

Vasculitis Foundation

P.O. Box 28660

Kansas City, MO 64188

USA

Tel: 8164368211

Fax: 8164368211

Tel: 8002779474

Email: vf@vasculitisfoundation.org

Internet: http://www.vasculitisfoundation.org



American Kidney Fund, Inc.

6110 Executive Boulevard

Suite 1010

Rockville, MD 20852

USA

Tel: 3018813052

Fax: 3018810898

Tel: 8006388299

Email: helpline@kideyfund.org

Internet: http://www.kidneyfund.org



National Kidney Foundation

30 East 33rd Street

New York, NY 10016

Tel: (212)889-2210

Fax: (212)689-9261

Tel: (800)622-9010

Email: info@kidney.org

Internet: http://www.kidney.org



American Lung Association

61 Broadway, 6th Floor

New York, NY 10006

USA

Tel: 2123158700

Fax: 2123158870

Tel: 8005864872

Internet: http://www.lungusa.org



NIH/National Heart, Lung and Blood Institute Information Center

P.O. Box 30105

Bethesda, MD 20824-0105

Tel: (301)592-8573

Fax: (301)251-1223

Email: nhlbiinfo@rover.nhlbi.nih.gov



MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network

150 Custer Court

Green Bay, WI 54301-1243

USA

Tel: 9203365333

Fax: 9203390995

Tel: 8773365333

Email: mums@netnet.net

Internet: http://www.netnet.net/mums/



Autoimmune Information Network, Inc

PO Box 4121

Brick, NJ 08723

Tel: (732)262-0450

Fax: (732)262-0450

Email: autoimmunehelp@aol.com

Internet: http://www.aininc.org



European Society for Immunodeficiencies (ESID)

c/o Dr. Esther de Vries

Jeroen Bosch Hospital

Dept. Paediatrics

P.O. Box 90153

Hertogenbosch, 5200 ME's

Netherlands

Tel: +31 73-6992965

Fax: +31 73-6992948

Email: info@esid.org

Internet: http://www.esid.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  7/23/2007

Copyright  1986, 1988, 1989, 1996, 1997, 1998, 1999, 2001, 2004, 2005, 2007 National Organization for Rare Disorders, Inc.

Last updated:	July 23, 2007