Signs of neuroleptic malignant syndrome

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Signs of neuroleptic malignant syndrome

Neuroleptic malignant syndrome is a life-threatening reaction that occurs from taking antipsychotic medications. The exact cause of this syndrome is not known. However, it may occur when antipsychotic medications cause a person's body temperature regulating center to function improperly.

The first signs of neuroleptic malignant syndrome include:

High fever, between and .
Fast and/or irregular heartbeat.
Rapid breathing.
Severe sweating.

If treatment is not sought, more severe symptoms develop and include:

Tight and inflexible muscles.
Changes in alertness.
Blood pressure changes (either lower or higher than normal).
Shakiness.
Seizures.

People with neuroleptic malignant syndrome who do not get treatment can die from complications of the syndrome. Complications include absence of breathing, kidney failure, and life-threatening body fluid and chemical imbalances.

Sometimes people who have a fever and changes in their heart and breathing patterns think they have the flu. People who take antipsychotic medications and develop these symptoms need to be seen by a health professional.

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Author	Jeannette Curtis
Editor	Susan Van Houten, RN, BSN, MBA
Associate Editor	Tracy Landauer
Associate Editor	Pat Truman, MATC
Primary Medical Reviewer	Kathleen Romito, MD - Family Medicine
Specialist Medical Reviewer	Lisa S. Weinstock, MD - Psychiatry
Last Updated	February 5, 2008

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Last updated:	February 05, 2008
Author:	Jeannette Curtis
Reviewed By:	Kathleen Romito, MD - Family Medicine, Lisa S. Weinstock, MD - Psychiatry
Editors:	Susan Van Houten, RN, BSN, MBA, Pat Truman, MATC

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