Side effects of multiple sclerosis medications


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Side effects of multiple sclerosis medications


Disease-modifying medications for multiple sclerosis (MS) can have significant side effects.

Interferon beta

Side effects of treatment with interferon beta-1a (Avonex and Rebif) and interferon beta-1b (Betaseron) include:

  • Flulike symptoms (such as fatigue, chills, fever, and muscle aches) for 1 to 2 days after an injection. These symptoms, which can be debilitating for some people, often stop after 2 to 3 months of treatment. Taking a pain reliever such as ibuprofen or acetaminophen just before and after each injection may help reduce these symptoms.
  • Redness, swelling, or tenderness at the injection site. This is more common with Betaseron and Rebif. Taking a nonprescription pain reliever just before or after an injection can reduce this side effect.
  • Depression, anxiety, confusion, and eating and sleeping disturbances. These are not very common and may be related as much to MS as to the treatment. Talk to your doctor if these symptoms last more than a day or two.

Glatiramer acetate

Side effects of glatiramer acetate (Copaxone) may include:

  • Pain, redness, or swelling at the injection site (this occurs in most people).
  • Flushing.
  • Chest pain, rapid heartbeat, and shortness of breath.
  • Anxiety.
  • Tightness in the throat.

These side effects are rarely serious and usually go away on their own shortly after the injection. You may have one or several brief episodes of these effects during the course of treatment with glatiramer acetate.

Credits


Author Shannon Erstad, MBA/MPH
Editor Kathleen M. Ariss, MS
Associate Editor Michele Cronen
Associate Editor Pat Truman
Primary Medical Reviewer Kathleen Romito, MD

- Family Medicine
Specialist Medical Reviewer Barrie J. Hurwitz, MD

- Neurology
Last Updated March 23, 2006

Healthwise Logo
Last updated: March 23, 2006
Author: Shannon Erstad, MBA/MPH
Reviewed By: Kathleen Romito, MD - Family Medicine, Barrie J. Hurwitz, MD - Neurology
Editors: Kathleen M. Ariss, MS, Pat Truman

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