Preventive vaccination (pre-exposure prophylaxis) for rabies


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Preventive vaccination (pre-exposure prophylaxis) for rabies


A preventive vaccine for rabies is given in three shots over 21 days. Pre-exposure vaccination does not eliminate the need for postexposure treatment, but postexposure treatment is simpler and shorter for those who have received a vaccine before exposure to rabies.

Booster shots should be considered when an occupation or hobby involves continued exposure to the virus. But the risk of allergic reaction to the vaccine increases with each dose, so a booster shot should be given only when the antibody level from the previous vaccine drops below an acceptable level. This is determined by a lab test that measures the level of rabies antibodies in the system. The test is performed every 6 months to 2 years, depending on risk.

Credits


Author Caroline Rea, RN, BS, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Pat Truman, MATC
Primary Medical Reviewer William M. Green, MD - Emergency Medicine
Specialist Medical Reviewer W. David Colby IV, MSc, MD, FRCPC - Infectious Disease
Last Updated September 9, 2008

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Last updated: September 09, 2008
Author: Caroline Rea, RN, BS, MS
Reviewed By: William M. Green, MD - Emergency Medicine, W. David Colby IV, MSc, MD, FRCPC - Infectious Disease
Editors: Susan Van Houten, RN, BSN, MBA, Pat Truman, MATC

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