Preventing diabetic kidney disease


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Preventing diabetic kidney disease


Diabetes is the leading cause of kidney failure in the United States. Early detection of kidney damage increases your likelihood of preventing kidney failure. Regular visits to your health professional, periodic urine tests, and lifestyle changes may decrease your risk for developing kidney disease (diabetic nephropathy), preventing kidney failure.

You should minimize your risk factors, which include:

You cannot control some risk factors, such as age, race (African American or Native American), and other genetic factors. But you can reduce your risk for diabetic nephropathy by not smoking, controlling both your blood glucose and your blood pressure, losing weight, and having a yearly screening test for protein in your urine.

When the kidneys are damaged by diabetes, they cannot properly filter wastes from your body and they begin to eliminate an essential protein, albumin. Your health professional can monitor your urine for the amount of albumin you are losing and use this information to detect kidney damage as early as possible.

  • A microalbuminuria test detects very small amounts of protein in your urine, indicating early kidney damage. If you have small amounts of protein in your urine, your doctor will prescribe a medicine to slow the progression of the disease. Microalbuminuria also is a sign that you are at risk for heart disease.
  • A macroalbuminuria test can reveal large amounts of protein in the urine, indicating severe damage to the kidneys and possible kidney failure.

The difference between these two tests is shown in the table below.

Tests for urine protein

Test

What it detects

Next steps, if you test positive

Microalbuminuria

Extremely small amounts of protein in your urine: This suggests early kidney damage before it is noticeable on exam or by other tests. Microalbuminuria can develop years before kidney failure occurs.

  • Prevent progression of nephropathy by having a hemoglobin A1c of below 7% and by keeping your blood pressure at or below 130/80.
  • Reduce protein in the diet.
  • Start taking an angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB).
  • Avoid medicines, such as nonsteroidal anti-inflammatory drugs (NSAIDs), that can damage kidneys.
Macroalbuminuria

Larger amounts of protein in your urine; advanced kidney damage

  • Follow the above treatments.
  • If kidney damage is severe, begin dialysis.

Credits


Author Caroline Rea, RN, BS, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Michele Cronen
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Caroline S. Rhoads, MD - Internal Medicine
Specialist Medical Reviewer Matthew I. Kim, MD - Endocrinology & Metabolism
Last Updated August 14, 2007

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Last updated: August 14, 2007
Author: Caroline Rea, RN, BS, MS
Reviewed By: Caroline S. Rhoads, MD - Internal Medicine, Matthew I. Kim, MD - Endocrinology & Metabolism
Editors: Susan Van Houten, RN, BSN, MBA, Pat Truman, MATC

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