Myelodysplastic syndromes (MDS)


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Myelodysplastic syndromes (MDS)


Myelodysplastic syndromes (MDS) are a group of blood diseases that cause an abnormally low production of blood cells. MDS is more common in older adults and rare in children and may develop before the start of a more serious blood disease, acute myelogenous leukemia.

Symptoms of MDS include a decreased production of red blood cells (anemia) and bleeding caused by a decreased production of platelet cells (thrombocytopenia). Later symptoms include enlargement of the liver (hepatomegaly), enlargement of the spleen (splenomegaly), and swelling of the lymph nodes (lymphadenopathy).

Treatment of MDS depends on the severity of the disease and can include blood transfusions and chemotherapy.

Credits


Author Jeannette Curtis
Author Caroline Rea, RN, BS, MS
Editor Kathleen M. Ariss, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Tracy Landauer
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Patrice Burgess, MD - Family Medicine
Primary Medical Reviewer Adam Husney, MD - Family Medicine
Primary Medical Reviewer Kathleen Romito, MD - Family Medicine
Last Updated May 25, 2007

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Last updated: May 25, 2007
Author: Caroline Rea, RN, BS, MS
Reviewed By: Kathleen Romito, MD - Family Medicine
Editors: Susan Van Houten, RN, BSN, MBA, Pat Truman, MATC

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