Liquid-based collection methods for cervical cell evaluation
Liquid-based collection methods for cervical cell evaluation
Liquid-based methods for collecting cervical cells and preparing them for laboratory evaluation are now available.
A sample of cervical cells is collected during a Pap test, and the cells are then rinsed in a liquid vial instead of being smeared on slides. The vials are taken to the laboratory, and a thin layer of the specimen is put on slides for microscopic examination. Only a small portion of the sample is used for the slide, so the remainder of the cell sample can be used for any additional testing, such as a human papillomavirus (HPV) test.
Some studies show that this method may be more sensitive in identifying abnormal cervical cell changes. However, these methods can produce false-positive results just like standard Pap tests. Not all laboratories provide this testing, but liquid-based methods are becoming more widely used. These methods cost more than standard Pap testing.
Credits
| Author | Shannon Erstad, MBA/MPH |
| Editor | Kathleen M. Ariss, MS |
| Associate Editor | Denele Ivins |
| Associate Editor | Pat Truman, MATC |
| Primary Medical Reviewer | Joy Melnikow, MD, MPH - Family Medicine |
| Specialist Medical Reviewer | Barbara S. Apgar, MD, MS - Family Medicine, Women's Health |
| Specialist Medical Reviewer | Ross Berkowitz, MD - Obstetrics and Gynecology |
| Last Updated | January 12, 2007 |
| Last updated: | January 12, 2007 |
|---|---|
| Author: | Shannon Erstad, MBA/MPH |
| Reviewed By: | Joy Melnikow, MD, MPH - Family Medicine, Ross Berkowitz, MD - Obstetrics and Gynecology |
| Editors: | Kathleen M. Ariss, MS, Pat Truman, MATC |
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