Lactate dehydrogenase


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Lactate dehydrogenase


Lactate dehydrogenase (LDH) is a protein (enzyme) that speeds up chemical reactions in the body. It is found in red blood cells and in many organs, including the heart, liver, muscles, lungs, brain, and kidneys.

There are five different fractions of LDH (called isoenzymes): LDH-1, LDH-2, LDH-3, LDH-4, and LDH-5.

A blood test to measure LDH levels is done to check for damage to organs throughout the body. The amounts of each isoenzyme also may be measured to help determine what organ may be damaged. Some conditions that increase LDH levels include stroke, heart attack, anemia, and hepatitis.

Credits


Author Maria G. Essig, MS, ELS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Tracy Landauer
Primary Medical Reviewer Kathleen Romito, MD - Family Medicine
Specialist Medical Reviewer Brian D. O'Brien, MD - Internal Medicine
Last Updated April 17, 2008

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Last updated: April 17, 2008
Author: Maria G. Essig, MS, ELS
Reviewed By: Kathleen Romito, MD - Family Medicine, Brian D. O'Brien, MD - Internal Medicine
Editors: Susan Van Houten, RN, BSN, MBA, Tracy Landauer

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