Intravenous immunoglobulin (IVIG) for multiple sclerosis


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Intravenous immunoglobulin (IVIG) for multiple sclerosis


Intravenous immunoglobulin (IVIG) is a medication often used to boost the body's immune system and make it better able to fight disease. It is made from donated blood fluids.

At least one small study has shown that IVIG treatment may improve function in some people with relapses in relapsing-remitting MS.1 It does not seem to help slow the progression of MS.2

However, IVIG is extremely expensive, not widely available, and not considered practical for long-term treatment of MS. It sometimes may be used to treat a severe relapse if you either cannot take or do not respond to corticosteroids.

The safety of IVIG during pregnancy and breast-feeding is not known. Talk to your doctor if you are planning a pregnancy, if you are pregnant, or if you are breast-feeding.

References


Citations

  1. Nicholas R, Chataway J (2006). Multiple sclerosis, search date January 2006. Online version of BMJ Clinical Evidence. Also available online: http://www.clinicalevidence.com.

  2. Goodin DS, et al. (2002). Disease modifying therapies in multiple sclerosis: Report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology and the MS Council for Clinical Practice Guidelines. Neurology, 58(2): 169–178.

Credits


Author Monica Rhodes
Editor Kathleen M. Ariss, MS
Associate Editor Denele Ivins
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer Colin Chalk, MD, CM, FRCPC - Neurology
Last Updated February 28, 2008

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Last updated: February 28, 2008
Author: Monica Rhodes
Reviewed By: Anne C. Poinier, MD - Internal Medicine, Colin Chalk, MD, CM, FRCPC - Neurology
Editors: Kathleen M. Ariss, MS, Pat Truman, MATC

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