Infections and inflammation and coronary artery disease


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Infections and inflammation and coronary artery disease


Recent research has suggested that inflammation in the blood vessels is a risk factor for the development of atherosclerosis. This is because chemicals (known as biochemical markers) released by cells that line blood vessels may indicate the presence of inflammation. One biochemical marker, known as a C-reactive protein, is associated with an increased risk of coronary artery disease (CAD) and heart attack.1

Some infections may also trigger a heart attack in people who already have CAD.2 But a recent study found that taking antibiotics to prevent infections did not reduce the risk of having a heart attack in people that have been diagnosed with CAD.3

References


Citations

  1. Koenig W (2001). Inflammation and coronary artery disease: An overview. Cardiology in Review, 9(1): 31–35.

  2. Rupprecht HJ, et al. (2001). Impact of viral and bacterial infectious burdens on long-term prognosis in patients with coronary artery disease. Circulation, 104(1): 25–31.

  3. Grayston JT, et al. (2005). Azithromycin for the secondary prevention of coronary events. New England Journal of Medicine, 352(16): 1637–1645.

Credits


Author Robin Parks, MS
Editor Kathleen M. Ariss, MS
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Caroline S. Rhoads, MD - Internal Medicine
Specialist Medical Reviewer Stephen Fort, MD, MRCP, FRCPC - Interventional Cardiology
Last Updated May 14, 2007

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Last updated: May 14, 2007
Author: Robin Parks, MS
Reviewed By: Caroline S. Rhoads, MD - Internal Medicine, Stephen Fort, MD, MRCP, FRCPC - Interventional Cardiology
Editors: Kathleen M. Ariss, MS, Pat Truman, MATC

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