Henoch-Schonlein Purpura

Content provided by National Organization for Rare Disorders

Important

It is possible that the main title of the report Henoch-Schonlein Purpura is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

• Allergic Purpura
• Anaphylactoid Purpura
• Hemorrhagic Capillary Toxicosis
• Henoch-Schonlein Purpura
• Nonthrombocytopenic Idiopathic Purpura
• Peliosis Rheumatica
• Rheumatic Purpura
• Schonlein-Henoch Purpura
• HSP
• Allergic Vasculitis
• Leukocytoclastic Vasculitis

Disorder Subdivisions

• Henoch's Purpura
• Schonlein's Purpura

General Discussion

Henoch-Schonlein purpura is a rare inflammatory disease of the small blood vessels (capillaries) and is usually a self-limited disease. It is the most common form of childhood vascular inflammation (vasculitis) and results in inflammatory changes in the small blood vessels. The symptoms of Henoch-Schonlein purpura usually begin suddenly and may include headache, fever, loss of appetite, cramping abdominal pain, and joint pain. Red or purple spots typically appear on the skin (petechial purpura). Inflammatory changes associated with Henoch-Schonlein purpura can also develop in the joints, kidneys, digestive system, and, in rare cases, the brain and spinal cord (central nervous system).



In one form of the disorder, termed Schonlein's purpura, the skin and joints are affected but the gastrointestinal tract is not. In another form, known as Henoch's purpura, affected individuals have purplish spots on the skin and acute abdominal problems. People with Henoch's purpura are not affected by joint disease.



The exact cause of Henoh-Schonlein purpura is not fully understood, although research suggests that it may be an autoimmune disease or, in some rare cases, an extreme allergic reaction to certain offending substances (e.g., foods or drugs).

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Resources

Vasculitis Foundation

P.O. Box 28660

Kansas City, MO 64188

USA

Tel: 8164368211

Fax: 8164368211

Tel: 8002779474

Email: vf@vasculitisfoundation.org

Internet: http://www.vasculitisfoundation.org



American Kidney Fund, Inc.

6110 Executive Boulevard

Suite 1010

Rockville, MD 20852

USA

Tel: 3018813052

Fax: 3018810898

Tel: 8006388299

Email: helpline@kideyfund.org

Internet: http://www.kidneyfund.org



American Autoimmune Related Diseases Association, Inc.

22100 Gratiot Avenue

Eastpointe, MI 48021-2227

Tel: (586)776-3900

Fax: (586)776-3903

Tel: (800)598-4668

Email: aarda@aarda.org

Internet: http://www.aarda.org/



National Kidney Foundation

30 East 33rd Street

New York, NY 10016

Tel: (212)889-2210

Fax: (212)689-9261

Tel: (800)622-9010

Email: info@kidney.org

Internet: http://www.kidney.org



NIH/National Heart, Lung and Blood Institute Information Center

P.O. Box 30105

Bethesda, MD 20824-0105

Tel: (301)592-8573

Fax: (301)251-1223

Email: nhlbiinfo@rover.nhlbi.nih.gov



NIH/National Institute of Allergy and Infectious Diseases

6610 Rockledge Drive

MSC 6612

Bethesda, MD 20892-6612

Tel: (301)496-5717

Fax: (301)402-3573

TDD: (800)877-8339

Internet: http://www.niaid.nih.gov/



Platelet Disorder Support Association

135 Rollins Ave Suites

Rockville, MD 20852

USA

Tel: 3017706636

Fax: 3017706638

Tel: 8775283538

Email: pdsa@pdsa.org

Internet: http://www.pdsa.org



MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network

150 Custer Court

Green Bay, WI 54301-1243

USA

Tel: 9203365333

Fax: 9203390995

Tel: 8773365333

Email: mums@netnet.net

Internet: http://www.netnet.net/mums/



AutoImmunity Community



Tel: (919)-55-2-9057

Email: bandrews@autoimmunitycommunity.org

Internet: http://autoimmunitycommunity.org



Kidney & Urology Foundation of America, Inc.

152 Madison Ave.

Suite 201

New York, NY 10016

Tel: (212)629-9770

Fax: (212)629-5652

Tel: (800)633-6628

Email: info@kidneyurology.org

Internet: http://www.kidneyurology.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  4/25/2008

Copyright  1987, 1989, 1997, 2005 National Organization for Rare Disorders, Inc.

Last updated:	April 25, 2008