Genetic disorders and birth defects in multiple pregnancy

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Genetic disorders and birth defects in multiple pregnancy

Genetic disorders, such as Down syndrome or cystic fibrosis, and birth defects occur more frequently in multiple pregnancies than in pregnancies with one fetus. A group of deformities of the ankles and/or feet (clubfoot) is an example of a birth defect seen more commonly in multiple pregnancy.

Genetic disorders and birth defects occur more frequently in identical fetuses than in fraternal ones. In rare cases, problems occur when the genetic material (chromosomes) in the fertilized egg does not split evenly. This can result in severe mental or physical defects in one or more fetuses.

Conjoined (Siamese) twins occur rarely. This occurs when the egg does not split completely and the fetuses are partially joined.

Most health professionals generally recommend screening for genetic disorders for all pregnant women.

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Author	Debby Golonka, MPH
Editor	Kathe Gallagher, MSW
Associate Editor	Pat Truman, MATC
Primary Medical Reviewer	Adam Husney, MD - Family Medicine
Specialist Medical Reviewer	Gregory A L Davies, MD, FRCSC, FACOG - Maternal-Fetal Medicine
Last Updated	July 24, 2007

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Last updated:	July 24, 2007
Author:	Debby Golonka, MPH
Reviewed By:	Adam Husney, MD - Family Medicine, Gregory A L Davies, MD, FRCSC, FACOG - Maternal-Fetal Medicine
Editors:	Kathe Gallagher, MSW, Pat Truman, MATC

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