Cervical cancer survival rates
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Cervical cancer survival rates
Survival rates decrease as the stage of cervical cancer becomes more advanced and the cancer involves other body organs.1, 2
| Stage of cancer | Tissue involvement | Treatment | 5-year survival rate |
|---|---|---|---|
Microinvasive with minimal invasion into deeper cell layers | Cone biopsy or hysterectomy | 97% | |
Minimal invasion into deeper cell layers | Surgery or radiation plus chemotherapy | 70% to 85% | |
May extend beyond the cervix such as into the upper vagina, but not into the connective tissue surrounding the uterus or onto the pelvic wall | Surgery or radiation plus chemotherapy | 60% to 70% | |
Cancer involves the pelvic sidewall and lower vagina | Radiation and chemotherapy | 30% to 45% | |
Cancer has spread to other body organs (metastatic disease) | Radiation and chemotherapy | 12% to 18% |
Chemotherapy given at the same time as radiation treatment (chemoradiation) improves survival rates in stages IB, IIA, IIB, IIIA, IIIB, and stage IVA cervical cancer.3, 4, 5
About 35% of women with cervical cancer will have persistent or recurrent disease.6 Recurrences usually develop in the first 2 years after initial treatment, so close monitoring is recommended.7
References
Citations
Bristow RE (2003). Cervical cancer. In JR Scott et al., eds., Danforth's Obstetrics and Gynecology, 9th ed., pp. 923–939. Philadelphia: Lippincott Williams and Wilkins.
Holschneider CH (2003). Premalignant and malignant disorders of the uterine cervix. In AH DeCherney, L Nathan, eds., Current Obstetric and Gynecologic Diagnosis and Treatment, 9th ed., pp. 894–915. New York: Lange Medical/McGraw-Hill.
Waggoner SE (2003). Cervical cancer. Lancet, 361: 2217–2225.
Thigpen T (2003). The role of chemotherapy in the management of carcinoma of the cervix. Cancer Journal, 9(5): 425–432.
Eifel PJ, et al. (2004). Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: An update of Radiation Therapy Oncology Group Trial (RTOG) 90-01. Journal of Clinical Oncology, 22(5): 872–880.
Greer BE, Koh WJ. (2002). Diagnosis and treatment of cervical carcinomas. American College of Obstetricians and Gynecologists, 99(5): 855–866.
Janicek MF, Averette HE. (2001). Cervical cancer: Prevention, diagnosis, and therapeutics. CA, A Cancer Journal for Clinicians, 51: 92–114.
Credits
| Author | Shannon Erstad, MBA/MPH |
| Author | Merrill Hayden |
| Editor | Alison Allen |
| Editor | Kathleen M. Ariss, MS |
| Editor | Cynthia Tank |
| Associate Editor | Michele Cronen |
| Associate Editor | Pat Truman |
| Primary Medical Reviewer | Joy Melnikow, MD, MPH - Family Medicine |
| Primary Medical Reviewer | Kathleen Romito, MD - Family Medicine |
| Specialist Medical Reviewer | Kevin Holcomb, MD - Gynecologic Oncology |
| Last Updated | September 20, 2006 |
| Last updated: | September 20, 2006 |
|---|---|
| Author: | Merrill Hayden |
| Reviewed By: | Kathleen Romito, MD - Family Medicine, Kevin Holcomb, MD - Gynecologic Oncology |
| Editors: | Cynthia Tank, Pat Truman |
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