Antiphospholipid antibody syndrome from lupus
Antiphospholipid antibody syndrome from lupus
About 1 in 3 people with lupus produce an antibody that attacks certain blood-clotting factors, which can cause the blood to clot easily.1 This condition, called antiphospholipid antibody syndrome, can lead to mild or severe blood-clotting complications, including:
- Stroke, transient ischemic attack (TIA), or heart attack.
- Deep vein thrombosis or pulmonary embolism.
- Multi-infarct dementia.
- Gangrene of fingers or toes.
- Kidney disease.
- Preeclampsia, premature birth, and miscarriage or stillbirth, apparently caused by blood circulation problems in the placenta.
Antiphospholipid antibodies can be detected with a blood test. When diagnosed, the condition is usually treated with anticoagulants. Pregnant women with antiphospholipid antibody syndrome require close monitoring.
References
Citations
Crow MK (2008). Systemic lupus erythematosus. In L Goldman, D Ausiello, eds., Cecil Textbook of Medicine, 23rd ed., pp. 2022–2032. Philadelphia: Saunders Elsevier.
Credits
| Author | Shannon Erstad, MBA/MPH |
| Editor | Kathleen M. Ariss, MS |
| Associate Editor | Michele Cronen |
| Associate Editor | Denele Ivins |
| Associate Editor | Pat Truman, MATC |
| Primary Medical Reviewer | Adam Husney, MD - Family Medicine |
| Primary Medical Reviewer | Anne C. Poinier, MD - Internal Medicine |
| Specialist Medical Reviewer | Stanford M. Shoor, MD - Rheumatology |
| Last Updated | May 13, 2008 |
| Last updated: | May 13, 2008 |
|---|---|
| Author: | Shannon Erstad, MBA/MPH |
| Reviewed By: | Anne C. Poinier, MD - Internal Medicine, Stanford M. Shoor, MD - Rheumatology |
| Editors: | Kathleen M. Ariss, MS, Pat Truman, MATC |
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