Fashion designer Liz Lange opens up about her personal battle with cervical cancer.
Courtesy of Liz Lange
In 2001, celebrity maternity-wear designer Liz Lange launched a new product line with Nike, closed a six-year deal with Target and put together a show for fashion week -- all while battling cervical cancer. Lange and Dr. Ginger J. Gardner, a spokesperson for the Gynecologic Cancer Foundation, sat down with AOL Health to discuss cervical cancer, the dangers of human papillomavirus (HPV) and what helped save Lange's life.Read the interview below.
10 Anti-Cancer Foods
Anti-Cancer Superfoods: Do They Really Work?
Provided by Caring.com
The short answer to this question is -- drum roll, please -- yes. They really do. While studies are ongoing, and in many cases experts still don't know exactly how these superfoods work, there's strong evidence that certain fruits and vegetables rich in plant-based nutrients can both prevent tumors from starting and halt their growth. Here, the top foods to work into the family diet to cut cancer risk or help those with cancer recover.
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Turmeric
The orange-yellow spice turmeric, best known for its role in Indian curries and other Asian dishes, fights cancer because of an active ingredient, curcumin, that's a powerful antioxidant. Researchers at Ohio State University in Columbus reviewed numerous animal studies and concluded that curcumin demonstrated anti-cancer effects at virtually all stages of tumor development. Researchers in France and Britain also have been studying curcumin's action in the laboratory and concluded that it prevents and slows tumor cell growth. Watch out, though; according to the American Cancer Society, turmeric made certain anti-cancer drugs less effective when studied in animals and test tubes. Cancer patients shouldn't add a lot of turmeric to their diets or take curcumin supplements without talking to their doctors first.
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Blueberries, Acai Berries, Raspberries, and Cranberries
The rich, dark colors of blueberries, Brazilian acai berries, raspberries and cranberries come from phytochemicals that protect against numerous types of cancer. Most recently, researchers at the University of Florida found that the active ingredient in acai berries destroyed cancer cells when tested in cell cultures. And blueberries and muscadine grapes contain compounds that recent research shows cause cancer cells in the liver to self-destruct. In studies particularly important to women, cranberries have recently been discovered to be an important weapon in the fight against deadly ovarian cancer. Studies reported at the annual meeting of the American Chemical Society found that ovarian cancer cells that were becoming resistant to platinum chemotherapy -- the standard of care for ovarian cancer -- became six times more sensitive when exposed to a compound in cranberries. The anti-cancer properties of all these berries are so strong that researchers have developing concentrated supplements and other products such as purees and concentrates.
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Green Tea
One of the first plant-based chemicals to be studied for its anti-cancer properties, catechins -- the chemicals in green tea -- have been known for some time to prevent and reduce recurrence of breast and other cancers. With this particular chemical, experts even know why: a chemical known as EGCG inhibits breast tumor growth, a University of Mississippi study shows. Just two cups a day is enough to do the trick.
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Garlic
Numerous studies over the years (more than 30 different studies to date) have documented the anti-cancer properties of garlic. The strongest evidence so far has focused on digestive cancers, but garlic appears to protect against all types of cancer, including breast and prostate. According to the National Cancer Institute, an analysis of seven different large-scale population studies showed that the more raw and cooked garlic a person consumed, the lower his risk of stomach and colorectal cancer; one study found that middle-aged women who regularly consumed garlic had a 50 percent lower risk of developing colon cancer. Scientists have isolated two active ingredients in garlic, allicin and allyl sulfur, and demonstrated that they prevent and fight cancer in both animals and humans; you can take garlic in supplement form but the capsules must be enteric-coated to protect these active ingredients. Add crushed, fresh garlic to your meals whenever possible; some experts also recommend waiting 15 minutes between peeling and chopping the garlic to get the full effects of the active compounds.
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Broccoli and Cabbage
British researchers made headlines last year with a study that showed that men with early signs of developing prostate cancer prevented tumor growth by eating broccoli four times a week. Other studies have shown anti-cancer benefits from eating cabbage, brussels sprouts, and other cruciferous vegetables.
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Onions and Leeks
According to the National Institutes of Health, studies of people from Southern Europe who eat a diet high in garlic and onions show a direct relationship between high consumption of "allium" vegetables (all types of garlic, onions, and leeks) and reduced risk of many common cancers.
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Tomatoes
Harvard researcher Edward Giovannucci reviewed 72 different studies published by the National Cancer Institute, and concluded that lycopene, the active chemical in tomatoes, lowered the risk of many different cancers, particularly prostate, breast, lung and colon cancer. Subsequently, the FDA conducted a review of its own and disagreed, refusing food companies' request to label tomato products with an anti-cancer health promotion message. However, many experts believe the FDA's process was flawed and that tomatoes will be vindicated by further studies. The good news: cooking tomatoes seems to enhance the effects of lycopene, qualifying tomato-based spaghetti sauce as a nutritional powerhouse.
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Soy
The active ingredient in soy is genistein, which is a phytoestrogen that protects against hormone-dependent cancers. It's also a powerful inhibitor of several proteins that are implicated in the uncontrolled growth of cancer cells. To get the anti-cancer benefits of soy, you need to consume about 50 grams per day of the whole food, such as raw fresh soybeans, known as edamame, dry roasted soybeans, or tofu. The research to date shows that supplements containing isoflavones don't work with the same action as soybeans themselves and in fact can be bad for you rather than good.
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Resveratrol
The hype about red wine centers on an antioxidant called resveratrol that's present in grapes and grape juice, but is most concentrated in red wine. Numerous studies show that resveratrol possesses powerful anti-cancer activity. Teams at several universities and cancer centers are studying resveratrol's effects against specific types of cancer. Most recently, a University of Nebraska study published in Cancer Prevention Research demonstrated that resveratrol suppresses the abnormal cell growth that leads to most types of breast cancer. Breast cancer is fueled by estrogen, and resveratrol acts to block the action of the estrogen, preventing it from feeding tumor growth. Previously, research conducted at the University of Alabama at Birmingham showed that mice fed a diet enriched with resveratrol had an 87 percent reduction in their risk of developing prostate tumors of the most dangerous kind.
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AOL Health: Why has it taken you so long to talk to about your battle with cervical cancer? And why are you talking about it now?
Liz Lange: It took me awhile because, frankly, it was a painful,
painful time in my life and it was something that I really wasn't
comfortable talking about until I had a little bit more distance
between me and the whole situation, the treatment, the diagnosis. But
over the last year or so I've just felt compelled. There was a study
done recently that showed that 89 percent of women don't know or don't
believe that they're at risk for exposure to HPV, but we know that
that's actually not true. Eighty percent of women will be exposed to
HPV in their lifetime, and 30 women a day get diagnosed with cervical
cancer. And since it was a screening, the Pap test that actually saved my life, I just feel, how could I not, at this point, share my story and possibly help to save other lives.
AOL Health: Let's start at the beginning. Why did you first go to the doctor? Was it for an annual check-up?
LL: Yes. Actually, the beginning -- it was 2001, I was 35 years
old, I had a two-and-a-half year-old son at the time, and an
eight-month-old daughter. I was one of those people who went annually
to my gynecologist, so I went for my normal exam, and she took a Pap
test, which was something that she was always doing, but frankly I was
one of those people who really didn't even know why. I didn't ask any
questions. Luckily, thankfully, I did keep up with my visits and I had
a doctor who was good and who did these sorts of screenings. But it was
just completely routine. I breezed in and breezed out, and about a week
later my phone rang.
Looking back on it now, I always laugh to think, because I guess you
don't want to get a call from your doctor after you've been for a
visit, but I didn't know that then. And, you know, it led to her
telling me that the Pap smear had been -- I don't remember her words --
but sort of "funny" or "off" and that they wanted to do a biopsy, which
was very, very scary. Just the word biopsy.
The biopsy ended up showing something that's called high-grade
dysplasia. That's something that needs to be removed, but my
understanding is that's not cancer.
It wasn't a terribly scary diagnosis for me. I wasn't terribly scared
about it at the time. I was very, very busy at the time. I was doing a
fashion show. We had just partnered with Nike, and we were launching
our new product line. I was negotiating with Target for another product
line, so it was a very busy time. But I did, again, thankfully, take
care of getting the dysplasia removed. After that was removed, the
doctor biopsied that dysplasia that had been removed from my body.
Dr. Ginger J. Gardner: A portion of the cervix can be removed
when there are precancerous cells, which is also termed high-grade
dysplasia. She had a portion of the cervix removed, and obviously,
anytime we remove tissue we automatically send it for analysis. The
pathologic analysis demonstrated not just the pre-cancerous cells but
also cancerous cells.
LL: And that's how I got the diagnosis. The personal side of it
is that I remember very well that when I was done with this dysplasia
removal that my doctor said, "Oh we'll get back to you about the
results of this in a week or so." And I remember thinking, The results
of this? We already have the results. That's why we're doing this.
You'll never forget certain things. It was Columbus Day of that year,
2001, that I got the call for my doctor. And that was, in a way, the
day that I feel like my life changed forever. That led to surgery,
pretty major surgery. I had a hysterectomy. It was followed up with a
course of chemo and radiation
that were done together, which makes the whole treatment, in terms of
effects, it was hard. That was probably a six-month span. [After that,]
I considered myself cured.
Next: The Difference Between Cured and Remission









